Endocrine Abstracts

This study investigated the action of ferulic acid (FA) on the regulation of insulin sensitivity in high-fat diet (HFD)-induced obese mice. The ICR mice were fed with HFD (45 kcal% lard fat) for 16 weeks. Over the last 8 weeks of HFD feeding, these obese mice were orally administered with FA at doses of 25 and 50 mg/kg/day. At the end of all treatments, the epididymal fat, pancreas and hypothalamus were removed for analysis of biochemical parameters and expression of proteins....